Causes of death in a nationwide cohort of community-dwellers with Alzheimer's disease.

ABSTRACT:

Background

Alzheimer's disease (AD) is related to higher mortality but it is not entirely evident which causes of death explain this. The objective of this study was to assess the causes of death in a nationwide cohort of clinically verified AD cases and compare the causes to a matched comparison cohort without AD.

Methods

Cohort of all community-dwellers with clinically verified AD residing in Finland on 31 December 2005 (n = 27,948) and a matched comparison cohort without AD (n = 27,948). Mortality (2006-2012, n = 30,641, 54.8%) and causes of death were obtained from register. Cause of death was ascertained with clinical examination (87.3% of deaths), forensic (8.0%) or medical autopsy (4.7%).

Results

In AD cohort, the most common causes were diseases of the nervous

SUBMITTER: Tolppanen AM 

PROVIDER: S-EPMC7607696 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature