Trends in disease burden of chronic myeloid leukemia at the global, regional, and national levels: a population-based epidemiologic study.

ABSTRACT:

Background

Outcomes of chronic myeloid leukemia (CML) has been improved dramatically in the past two decades, but survival levels of CML patients varied in regions. Comprehensive epidemiological research is necessary to evaluate the global burden of CML.

Methods

All data used in our study came from the Global Burden of Disease (GBD) study 2017. Incidence cases, death cases, disability-adjusted life-years (DALYs), and its corresponding age-standardized rate between 1990 to 2017 were used to describe the distribution of CML burden, according to age, sex, social-demographic index (SDI), and countries. Data about attributable risk factors contributing to CML deaths and DALYs were also extracted and analyzed.

Results

Globally, the disease burden of CML gradually decreased

SUBMITTER: Ning L 

PROVIDER: S-EPMC7607878 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature