The relationship between body mass index and health-related quality of life in COPD: real-world evidence based on claims and survey data.

ABSTRACT:

Background

Body mass index (BMI) is an important parameter associated with mortality and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD). However, informed guidance on stratified weight recommendations for COPD is still lacking. This study aims to determine the association between BMI and HRQoL across different severity grades of COPD to support patient management.

Methods

We use conjunct analysis of claims and survey data based on a German COPD disease management program from 2016 to 2017. The EQ-5D-5L visual analog scale (VAS) and COPD Assessment Test (CAT) are used to measure generic and disease-specific HRQoL. Generalized additive models with smooth functions are implemented to evaluate the relationship between BMI and HRQoL, strati

SUBMITTER: Huber MB 

PROVIDER: S-EPMC7607880 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature