Ontology highlight
ABSTRACT:
SUBMITTER: Zohar T
PROVIDER: S-EPMC7608014 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Zohar Tomer T Loos Carolin C Fischinger Stephanie S Atyeo Caroline C Wang Chuangqi C Slein Matthew D MD Burke John J Yu Jingyou J Feldman Jared J Hauser Blake Marie BM Caradonna Tim T Schmidt Aaron G AG Cai Yongfei Y Streeck Hendrik H Ryan Edward T ET Barouch Dan H DH Charles Richelle C RC Lauffenburger Douglas A DA Alter Galit G
Cell 20201103 6
The urgent need for an effective SARS-CoV-2 vaccine has forced development to progress in the absence of well-defined correlates of immunity. While neutralization has been linked to protection against other pathogens, whether neutralization alone will be sufficient to drive protection against SARS-CoV-2 in the broader population remains unclear. Therefore, to fully define protective humoral immunity, we dissected the early evolution of the humoral response in 193 hospitalized individuals ranging ...[more]