Using prefrontal transcranial direct current stimulation (tDCS) to enhance proactive cognitive control in schizophrenia.

ABSTRACT: The goal of this study was to use transcranial direct current stimulation (tDCS) to examine the role of the prefrontal cortex (PFC) in neural oscillatory activity associated with proactive cognitive control in schizophrenia. To do so, we tested the impact of PFC-targeted tDCS on behavioral and electrophysiological markers of proactive cognitive control engagement in individuals with schizophrenia. Using a within-participants, double-blinded, sham-controlled crossover design, we recorded EEG while participants with schizophrenia completed a proactive cognitive control task (the Dot Pattern Expectancy (DPX) Task), after receiving 20 min of active prefrontal stimulation at 2 mA or sham stimulation. We hypothesized that active stimulation would enhance proactive cognitive control, leading to c

SUBMITTER: Boudewyn MA 

PROVIDER: S-EPMC7608454 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature