Ontology highlight
ABSTRACT:
SUBMITTER: Shi H
PROVIDER: S-EPMC7608651 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Shi Honglue H Rangadurai Atul A Abou Assi Hala H Roy Rohit R Case David A DA Herschlag Daniel D Yesselman Joseph D JD Al-Hashimi Hashim M HM
Nature communications 20201102 1
Biomolecules form dynamic ensembles of many inter-converting conformations which are key for understanding how they fold and function. However, determining ensembles is challenging because the information required to specify atomic structures for thousands of conformations far exceeds that of experimental measurements. We addressed this data gap and dramatically simplified and accelerated RNA ensemble determination by using structure prediction tools that leverage the growing database of RNA str ...[more]