Estimating the Year Each State in the United States Will Achieve the World Health Organization's Elimination Targets for Hepatitis C.

ABSTRACT:

Introduction

Although hepatitis C virus (HCV) infection remains a major clinical, economic, and societal burden, the development of curative antiviral therapy may accelerate the path toward elimination. This analysis assessed the progress of United States (US) states towards achieving the World Health Organization's (WHO) 2030 HCV elimination targets for incidence, mortality, diagnosis, and treatment.

Methods

A previously published Markov model was used to simulate HCV progression over time to estimate the path to HCV elimination in each state based on prevalence, annual treatment, and diagnosis inputs from two large US laboratory datasets from January 2013 to December 2017. State-specific fibrosis stage restrictions on treatment in 2017 were included. The model estimated th

SUBMITTER: Sulkowski M 

PROVIDER: S-EPMC7609357 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature