Prediction of culture-positive sepsis and selection of empiric antibiotics in critically ill patients with complicated intra-abdominal infections: a retrospective study.

ABSTRACT:

Purpose

To compare the mortality rates between culture-positive and culture-negative sepsis in complicated intra-abdominal infections (cIAI) and investigate the predictors of culture-positivity and their causative microorganisms.

Materials and methods

The medical records of 1581 adult patients who underwent emergency gastrointestinal surgery between January 2013 and December 2018 were reviewed retrospectively. A total of 239 patients with sepsis or septic shock who were admitted to an emergency department, underwent emergency surgery for cIAI, and needed postoperative intensive care unit care were included and divided into two groups according to their initial blood and peritoneal culture results.

Results

Among the 239 patients, 200 were culture-negative and 39 were c

SUBMITTER: Sim J 

PROVIDER: S-EPMC7609359 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature