Succinate dehydrogenase gene as a marker for studying Blastocystis genetic diversity.

ABSTRACT: Blastocystis has been reported as the most common eukaryotic microorganism residing in the intestines of both humans and animals, with a prevalence of up to 100% in some populations. Since this is a cryptic species, sequence polymorphism are the single strategy to analyses its genetic diversity, being traditionally used the analysis of ssu rRNA gene sequence to determine alleles and subtypes (STs) for this species. This multicopy gene has shown high diversity among different STs, making necessary to explore other genes to assess intraspecific diversity. This study evaluated the use of a novel genetic marker, succinate dehydrogenase (SDHA), for the typing and evaluation of the genetic diversity and genetic population structure of Blastocystis. In total, 375 human

SUBMITTER: Higuera A 

PROVIDER: S-EPMC7609450 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature