Bladder bacterial diversity differs in continent and incontinent women: a cross-sectional study.

ABSTRACT:

Background

Since the discovery of the bladder microbiome (urobiome), interest has grown in learning whether urobiome characteristics have a role in clinical phenotyping and provide opportunities for novel therapeutic approaches for women with common forms of urinary incontinence.

Objective

This study aimed to test the hypothesis that the bladder urobiome differs among women in the control cohort and women affected by urinary incontinence by assessing associations between urinary incontinence status and the cultured urobiome.

Study design

With institutional review board oversight, urine specimens from 309 adult women were collected through transurethral catheterization. These women were categorized into 3 cohorts (continent control, stress urinary incontinence [SUI], a

SUBMITTER: Price TK 

PROVIDER: S-EPMC7609606 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature