Novel Method for Osmotic Conductance to Glucose in Peritoneal Dialysis.

ABSTRACT:

Introduction

The osmotic conductance to glucose (OCG) is a crucial determinant of ultrafiltration (UF) in peritoneal dialysis (PD) patients and can be used to monitor membrane integrity in patients on long-term PD. It has been proposed that OCG can be assessed based on drained volumes in 2 consecutive 1-hour glucose dwells, usually 1.5% and 4.25% glucose, in a so-called double mini-peritoneal equilibration test (dm-PET). However, recent data indicated that the dm-PET provides a poor estimate of OCG unless the residual volume (RV) is taken into account. We introduce an easy, robust, and accurate method to measure OCG and compare it with conventional methods.

Methods

In a prospective cohort of 21 PD patients, a modified version of the dm-PET was performed, along with the deter

SUBMITTER: Martus G 

PROVIDER: S-EPMC7610002 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature