Mortality due to cancer treatment delay: systematic review and meta-analysis.

ABSTRACT:

Objective

To quantify the association of cancer treatment delay and mortality for each four week increase in delay to inform cancer treatment pathways.

Design

Systematic review and meta-analysis.

Data sources

Published studies in Medline from 1 January 2000 to 10 April 2020.

Eligibility criteria for selecting studies

Curative, neoadjuvant, and adjuvant indications for surgery, systemic treatment, or radiotherapy for cancers of the bladder, breast, colon, rectum, lung, cervix, and head and neck were included. The main outcome measure was the hazard ratio for overall survival for each four week delay for each indication. Delay was measured from diagnosis to first treatment, or from the completion of one treatment to the start of the next. The primary analysis onl

SUBMITTER: Hanna TP 

PROVIDER: S-EPMC7610021 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature