Risk assessment of nitrate and nitrite in feed.

ABSTRACT: The European Commission asked EFSA for a scientific opinion on the risks to animal health related to nitrite and nitrate in feed. For nitrate ion, the EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) identified a BMDL ₁₀ of 64 mg nitrate/kg body weight (bw) per day for adult cattle, based on methaemoglobin (MetHb) levels in animal's blood that would not induce clinical signs of hypoxia. The BMDL ₁₀ is applicable to all bovines, except for pregnant cows in which reproductive effects were not clearly associated with MetHb formation. Since the data available suggested that ovines and caprines are not more sensitive than bovines, the BMDL ₁₀ could also be applied to these species. Highest mean exposure estimates of 53 and 60 mg nitrate/kg bw per day

SUBMITTER: EFSA Panel on Contaminants in the Food Chain (CONTAM) 

PROVIDER: S-EPMC7610142 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature