Ultra-high field magnetic resonance imaging parameter mapping in the posterior horn of ex vivo human menisci.

ABSTRACT:

Objective

To investigate the relationship between meniscus magnetic resonance (MR) relaxation parameters and meniscus degradation through quantitative imaging of ex vivo posterior horns of menisci from subjects with and without knee osteoarthritis (OA).

Design

We sampled medial and lateral menisci from ten medial compartment knee OA patients (mean age 63 years) undergoing total knee replacement and from ten deceased donors (references, mean age 51 years). MR relaxation parameters T2*, T2 and T1 of the posterior horn were measured at a 9.4 T scanner. Comparisons were made between OA patients and references (with adjustment for age) as well as between medial and lateral menisci from the same knees.

Results

Mean values (standard deviation) of mean T2* were 13 (3.8), 6.9

SUBMITTER: Olsson E 

PROVIDER: S-EPMC7610687 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature