Interictal intracranial electroencephalography for predicting surgical success: The importance of space and time.

ABSTRACT:

Objective

Predicting postoperative seizure freedom using functional correlation networks derived from interictal intracranial electroencephalography (EEG) has shown some success. However, there are important challenges to consider: (1) electrodes physically closer to each other naturally tend to be more correlated, causing a spatial bias; (2) implantation location and number of electrodes differ between patients, making cross-subject comparisons difficult; and (3) functional correlation networks can vary over time but are currently assumed to be static.

Methods

In this study, we address these three challenges using intracranial EEG data from 55 patients with intractable focal epilepsy. Patients additionally underwent preoperative magnetic resonance imaging (MRI), intraoperat

SUBMITTER: Wang Y 

PROVIDER: S-EPMC7611164 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature