Ontology highlight
ABSTRACT:
SUBMITTER: Gruber AJ
PROVIDER: S-EPMC7611301 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Gruber Andreas J AJ Gypas Foivos F Riba Andrea A Schmidt Ralf R Zavolan Mihaela M
Nature methods 20180910 10
Sequencing of RNA 3' ends has uncovered numerous sites that do not correspond to the termination sites of known transcripts. Through their 3' untranslated regions, protein-coding RNAs interact with RNA-binding proteins and microRNAs, which regulate many properties, including RNA stability and subcellular localization. We developed the terminal exon characterization (TEC) tool ( http://tectool.unibas.ch ), which can be used with RNA-sequencing data from any species for which a genome annotation t ...[more]