Trajectories of Systolic Blood Pressure in Children: Risk Factors and Cardiometabolic Correlates.

ABSTRACT:

Objective

To identify systolic blood pressure (SBP) percentile trajectories in children and to describe the early-life risk factors and cardiometabolic correlates of those trajectories.

Study design

Using age-, sex-, and height-specific SBP percentiles based on the American Academy of Pediatrics reference, we examined SBP trajectories using latent class mixed models from ages 3 to 8 years (n = 844) from the Growing Up in Singapore Towards healthy Outcomes-study, a Singaporean mother-offspring cohort study. We analyzed associations between SBP trajectories and early-life risk factors using multinomial logistic regression and differences across trajectories in cardiometabolic outcomes using multiple linear regression.

Results

Children were classified into 1 of 4 SBP per

SUBMITTER: Yuan WL 

PROVIDER: S-EPMC7611585 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature