Maternal height, gestational diabetes mellitus and pregnancy complications.

ABSTRACT:

Aims

To explore the glucose-overload hypothesis of artefactual gestational diabetes (GDM) diagnosis in shorter women during oral glucose tolerance testing (OGTT), by investigating associations between height and maternal glycemia; and GDM and pregnancy complications in height-groups.

Methods

Women from GUSTO (n = 1100, 2009-2010) and NUH (n = 4068, 2017-2018) cohorts underwent a mid-gestation two and three time-point 75 g 2-hour OGTT, respectively. GDM-related complications (hypertensive disorders of pregnancy, preterm delivery, emergency cesarean section, neonatal intensive care unit admission, macrosomia, birthweight) were compared within shorter and taller groups, dichotomized by ethnic-specific median height.

Results

Using WHO-1999 criteria, 18.8% (GUSTO) to 22.9%

SUBMITTER: Chu AHY 

PROVIDER: S-EPMC7611603 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature