Modifiable early life exposures associated with adiposity and obesity in 3-year old children born to mothers with obesity.

ABSTRACT:

Background

Children born to mothers with obesity are at increased risk of obesity. Influences underlying this predisposition include in-utero exposures, genetic predisposition and a shared family environment. Effective intervention strategies are needed to prevent obesity in these high-risk children; this requires evaluation of modifiable pregnancy and early-life risk factors.

Objectives

To assess the individual and cumulative contributions of maternal and early-life modifiable exposures on childhood adiposity and obesity outcomes in 3-year-old children born to women with obesity.

Methods

We used adjusted regression to assess the individual and cumulative contributions of six exposures (early pregnancy BMI, excessive gestational weight gain, mode of infant feeding and

SUBMITTER: Dalrymple KV 

PROVIDER: S-EPMC7611818 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature