Differential relationships between parent-child DXA and pQCT bone measures: Results from the Southampton Women's Survey.

ABSTRACT:

Aim

To investigate the associations between indices of bone health in childhood and corresponding parental measures.

Methods

The Southampton Women's Survey characterised 12,583 non-pregnant women aged 20-34 years; 3158 subsequently had singleton live births. In a subset, dual-energy X-ray absorptiometry (DXA) measurements of bone area (BA), bone mineral content (BMC) and areal bone mineral density (aBMD) lumbar spine and total hip were obtained in the parent/offspring (aged 8-9 years) trios. Another subset of children (aged 6-7 years), and their parents, had peripheral quantitative computed tomography (pQCT; 4% and 38% tibia) measures. Using multivariable linear regression we examined relationships between mother/father and offspring, adjusting for parental age, habitual wal

SUBMITTER: Holroyd CR 

PROVIDER: S-EPMC7611825 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature