Pulmonary metastasectomy in colorectal cancer: health utility scores by EQ-5D-3L in a randomized controlled trial show no benefit from lung metastasectomy.

ABSTRACT:

Aim

The aim was to assess the health utility of lung metastasectomy in the treatment of patients with colorectal cancer (CRC) using the EQ-5D-3L questionnaire.

Methods

Multidisciplinary CRC teams at 14 sites recruited patients to a two-arm randomized controlled trial-Pulmonary Metastasectomy in Colorectal Cancer (PulMiCC). Remote randomization was used, stratified by site and with minimization for seven known confounders. Participants completed the EQ-5D-3L questionnaire together with other patient reported outcome measures at randomization and then again at 3, 6, 12 and 24 months. These were returned by post to the coordinating centre.

Results

Between December 2010 and December 2016, 93 participants were randomized, 91 of whom returned questionnaires. Survival and pa

SUBMITTER: Brew-Graves C 

PROVIDER: S-EPMC7612179 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature