Differential Mortality Risks Associated With PM2.5 Components: A Multi-Country, Multi-City Study.

ABSTRACT:

Background

The association between fine particulate matter (PM2.5) and mortality widely differs between as well as within countries. Differences in PM2.5 composition can play a role in modifying the effect estimates, but there is little evidence about which components have higher impacts on mortality.

Methods

We applied a 2-stage analysis on data collected from 210 locations in 16 countries. In the first stage, we estimated location-specific relative risks (RR) for mortality associated with daily total PM2.5 through time series regression analysis. We then pooled these estimates in a meta-regression model that included city-specific logratio-transformed proportions of seven PM2.5 components as well as meta-predictors derived from city-specific socio-economic and environmenta

SUBMITTER: Masselot P 

PROVIDER: S-EPMC7612311 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature