Takotsubo Syndrome: Pathophysiology, Emerging Concepts, and Clinical Implications.

ABSTRACT: Takotsubo syndrome is a condition characterized by acute transient left ventricular systolic dysfunction, which at presentation can be challenging to distinguish from acute myocardial infarction. Although previously thought to be a benign, self-limiting condition, recent studies have confirmed that patients with takotsubo syndrome have persistent subtle ongoing cardiac dysfunction, and many continue to have limiting symptoms despite restoration of left ventricular ejection fraction. Moreover, these patients have a substantial burden of morbidity and mortality, as well, with high rates of subsequent major adverse cardiovascular events that approach those of patients with acute coronary syndrome. The mechanisms behind this condition remain elusive. Despite substantial research, the medical c

SUBMITTER: Singh T 

PROVIDER: S-EPMC7612566 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature