Increasing Diagnostic Uncertainties in Children With In Utero HIV Infection.

ABSTRACT: We present a case of an in utero HIV-infected child, who on day 1 of life had a positive whole blood total nucleic acid test but viral load <20 RNA copies/mL. Dried blood spot total nucleic acid testing was negative on day 1, 10 and at 3 months, while on ART prophylaxis then positive at 5 months after prophylaxis ended. Retrospective peripheral blood mononuclear cells HIV DNA testing from day 1 of life was positive, confirming in utero infection.

SUBMITTER: Millar JR 

PROVIDER: S-EPMC7612888 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature