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Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition.


ABSTRACT:

SUBMITTER: Hidalgo-Mazzei D 

PROVIDER: S-EPMC7613090 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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<h4>Background</h4>Most people with bipolar disorder spend a significant percentage of their lifetime experiencing either subsyndromal depressive symptoms or major depressive episodes, which contribute greatly to the high levels of disability and mortality associated with the disorder. Despite the importance of bipolar depression, there are only a small number of recognised treatment options available. Consecutive treatment failures can quickly exhaust these options leading to treatment-resistan  ...[more]

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