Resting-State Network Patterns Underlying Cognitive Function in Bipolar Disorder: A Graph Theoretical Analysis.

ABSTRACT: Background: Synchronous and antisynchronous activity between neural elements at rest reflects the physiological processes underlying complex cognitive ability. Regional and pairwise connectivity investigations suggest that perturbations in these activity patterns may relate to widespread cognitive impairments seen in bipolar disorder (BD). Here we take a network-based perspective to more meaningfully capture interactions among distributed brain regions compared to focal measurements and examine network-cognition relationships across a range of commonly affected cognitive domains in BD in relation to healthy controls. Methods: Resting-state networks were constructed as matrices of correlation coefficients between regionally averaged resting-state time series from

SUBMITTER: McPhilemy G 

PROVIDER: S-EPMC7613113 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature