Anxiety disorders and age-related changes in physiology.

ABSTRACT:

Background

Anxiety disorders are leading contributors to the global disease burden, highly prevalent across the lifespan and associated with substantially increased morbidity and early mortality.

Aims

The aim of this study was to examine age-related changes across a wide range of physiological measures in middle-aged and older adults with a lifetime history of anxiety disorders compared with healthy controls.

Method

The UK Biobank study recruited >500 000 adults, aged 37-73, between 2006 and 2010. We used generalised additive models to estimate non-linear associations between age and hand-grip strength, cardiovascular function, body composition, lung function and heel bone mineral density in a case group and in a control group.

Results

The main data-set include

SUBMITTER: Mutz J 

PROVIDER: S-EPMC7613411 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature