Depth dose measurements in water for ¹¹C and ¹⁰C beams with therapy relevant energies.

ABSTRACT: Owing to the favorable depth-dose distribution and the radiobiological properties of heavy ion radiation, ion beam therapy shows an improved success/toxicity ratio compared to conventional radiotherapy. The sharp dose gradients and very high doses in the Bragg peak region, which represent the larger physical advantage of ion beam therapy, make it also extremely sensitive to range uncertainties. The use of β ⁺-radioactive ion beams would be ideal for simultaneous treatment and accurate online range monitoring through PET imaging. Since all the unfragmented primary ions are potentially contributing to the PET signal, these beams offer an improved image quality while preserving the physical and radiobiological advantages of the stable counterparts. The challenging production

SUBMITTER: Boscolo D 

PROVIDER: S-EPMC7613790 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature