Antibiofilm activity of nanosilver coatings against Staphylococcus aureus.

ABSTRACT: Implant infections due to bacterial biofilms constitute a major healthcare challenge today. One way to address this clinical need is to modify the implant surface with an antimicrobial nanomaterial. Among such nanomaterials, nanosilver is arguably the most powerful one, due to its strong and broad antimicrobial activity. However, there is still a lack of understanding on how physicochemical characteristics of nanosilver coatings affect their antibiofilm activity. More specifically, the contributions of silver (Ag)⁺ ion-mediated vs. contact-based mechanisms to the observed antimicrobial activity are yet to be elucidated. To address this knowledge gap, we produce here nanosilver coatings on substrates by flame aerosol direct deposition that allows for facile control of the coating

SUBMITTER: Geissel FJ 

PROVIDER: S-EPMC7613819 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature