Measuring adherence to antihypertensive medication using an objective test in older adults attending primary care: cross-sectional study.

ABSTRACT: Analysis of urine samples using liquid chromatography-tandem mass spectrometry (LC-MS/MS) has previously revealed high rates of non-adherence to antihypertensive medication. It is unclear whether these rates represent those in the general population. This study aimed to investigate whether it is feasible to collect urine samples in a primary care setting and analyse them using LC-MS/MS to detect non-adherence to antihypertensive medication. This study used a prospective, observational cohort design. Consecutive patients were recruited opportunistically from five general practices in UK primary care. They were aged ≥65 years with hypertension and had at least one antihypertensive prescription. Participants were asked to provide a urine sample for analysis of medication adherence. Samples we

SUBMITTER: Sheppard JP 

PROVIDER: S-EPMC7613908 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature