Manganese-Enhanced Magnetic Resonance Imaging in Takotsubo Syndrome.

ABSTRACT:

Background

Takotsubo syndrome is an acute cardiac emergency characterized by transient left ventricular systolic dysfunction typically following a stressful event. Despite its rapidly rising incidence, its pathophysiology remains poorly understood. Takotsubo syndrome may pass unrecognized, especially if timely diagnostic imaging is not performed. Defective myocardial calcium homeostasis is a central cause of contractile dysfunction and has not been explored in takotsubo syndrome. We aimed to investigate myocardial calcium handling using manganese-enhanced magnetic resonance imaging during the acute and recovery phases of takotsubo syndrome.

Methods

Twenty patients with takotsubo syndrome (63±12 years of age; 90% female) and 20 volunteers matched on age, sex, and cardiovascul

SUBMITTER: Singh T 

PROVIDER: S-EPMC7613919 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature