Attitudes towards risk-reducing early salpingectomy with delayed oophorectomy for ovarian cancer prevention: a cohort study.

ABSTRACT:

Objective

To determine risk-reducing early salpingectomy and delayed oophorectomy (RRESDO) acceptability and effect of surgical prevention on menopausal sequelae/satisfaction/regret in women at increased ovarian cancer (OC) risk.

Design

Multicentre, cohort, questionnaire study (IRSCTN:12310993).

Setting

United Kingdom (UK).

Population

UK women without OC ≥18 years, at increased OC risk, with/without previous RRSO, ascertained through specialist familial cancer/genetic clinics and BRCA support groups.

Methods

Participants completed a 39-item questionnaire. Baseline characteristics were described using descriptive statistics. Logistic/linear regression models analysed the impact of variables on RRESDO acceptability and health outcomes.

Main outcomes

SUBMITTER: Gaba F 

PROVIDER: S-EPMC7614715 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature