Major Depression and Survival in People With Cancer.

ABSTRACT:

Objective

The question of whether depression is associated with worse survival in people with cancer remains unanswered because of methodological criticism of the published research on the topic. We aimed to study the association in a large methodologically robust study.

Methods

We analyzed data on 20,582 patients with breast, colorectal, gynecological, lung, and prostate cancers who had attended cancer outpatient clinics in Scotland, United Kingdom. Patients had completed two-stage screening for major depression as part of their cancer care. These data on depression status were linked to demographic, cancer, and subsequent mortality data from national databases. We estimated the association of major depression with survival for each cancer using Cox regression. We adjusted

SUBMITTER: Walker J 

PROVIDER: S-EPMC7614901 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature