A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina.

ABSTRACT:

Background

Percutaneous coronary intervention (PCI) is frequently performed to reduce the symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in patients who are not receiving antianginal medication remains unknown.

Methods

We conducted a double-blind, randomized, placebo-controlled trial of PCI in patients with stable angina. Patients stopped all antianginal medications and underwent a 2-week symptom assessment phase before randomization. Patients were then randomly assigned in a 1:1 ratio to undergo PCI or a placebo procedure and were followed for 12 weeks. The primary end point was the angina symptom score, which was calculated daily on the basis of the number of angina episodes that occurred on a given day, the number of antianginal medic

SUBMITTER: Rajkumar CA 

PROVIDER: S-EPMC7615400 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature