Dataset Information
Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
Ontology highlight
ABSTRACT:
SUBMITTER: Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk
PROVIDER: S-EPMC7615958 | biostudies-literature | 2024 May
REPOSITORIES: biostudies-literature
Publications
Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
The lancet. Diabetes & endocrinology 20240327 5
<h4>Background</h4>Previous meta-analyses of summary data from randomised controlled trials have shown that statin therapy increases the risk of diabetes, but less is known about the size or timing of this effect, or who is at greatest risk. We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy.<h4>Methods</h4>We conducted a meta-analysis of individual participant data from randomised c ...[more]