Effect of developmental and adult diet composition on reproductive aging in Drosophila melanogaster.

ABSTRACT: Diet significantly affects reproductive outcomes across species, yet the precise effects of macronutrient compositions beyond caloric intake on reproductive aging are understudied. Existing literature presents conflicting views on the fertility impacts of nutrient-rich versus nutrient-poor developmental diets, underscoring a notable research gap. This study addresses these gaps by examining effects of isocaloric diets with varied protein-to-carbohydrate ratios during both developmental and adult stages on reproductive aging of a large, outbred Drosophila melanogaster population (n = ∼2100). Our results clearly demonstrate an age-dependent dietary impact on reproductive output, initially dominated by the developmental diet, then by a combination of developmental and adult diets in early to

SUBMITTER: Ruchitha BG 

PROVIDER: S-EPMC7616176 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature