Investigating harms of testing for ovarian cancer - psychological outcomes and cancer conversion rates in women with symptoms of ovarian cancer: A cohort study embedded in the multicentre ROCkeTS prospective diagnostic study.

ABSTRACT:

Objective

To investigate psychological correlates in women referred with suspected ovarian cancer via the fast-track pathway, explore how anxiety and distress levels change at 12 months post-testing, and report cancer conversion rates by age and referral pathway.

Design

Single-arm prospective cohort study.

Setting

Multicentre. Secondary care including outpatient clinics and emergency admissions.

Population

A cohort of 2596 newly presenting symptomatic women with a raised CA125 level, abnormal imaging or both.

Methods

Women completed anxiety and distress questionnaires at recruitment and at 12 months for those who had not undergone surgery or a biopsy within 3 months of recruitment.

Main outcome measures

Anxiety and distress levels measured using a

SUBMITTER: Kwong FL 

PROVIDER: S-EPMC7616335 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature