Tailored haemodynamic response function increases detection power of fMRI in awake dogs (Canis familiaris).

ABSTRACT: Functional magnetic resonance imaging (fMRI) of awake and unrestrained dogs (Canis familiaris) has been established as a novel opportunity for comparative neuroimaging, promising important insights into the evolutionary roots of human brain function and cognition. However, data processing and analysis pipelines are often derivatives of methodological standards developed for human neuroimaging, which may be problematic due to profound neurophysiological and anatomical differences between humans and dogs. Here, we explore whether dog fMRI studies would benefit from a tailored dog haemodynamic response function (HRF). In two independent experiments, dogs were presented with different visual stimuli. BOLD signal changes in the visual cortex during these experiments were used for (a) the identi

SUBMITTER: Boch M 

PROVIDER: S-EPMC7616344 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature