Outbreak of chikungunya virus in a vulnerable population of Sergipe, Brazil-A molecular and serological survey.

ABSTRACT:

Background

Chikungunya virus (CHIKV) is a re-emerging arbovirus that is causing outbreaks in several countries of the Americas. The virus was introduced in Brazil in 2014, and since then, several Brazilian states have notified autochthonous cases.

Objectives

Provide additional evidence on a CHIKV outbreak and an outline of the laboratory and clinical profile of symptomatic patients in Sergipe, Brazil.

Study design

In February 2016, we collected 142 serum samples from symptomatic patients for arboviruses in Sergipe, Brazil. All samples were submitted to qRT-PCR for the emerging arboviruses circulating in Brazil - ZIKV, CHIKV, and DENV - and later submitted to the immunoenzymatic assay. RNA positive samples were randomly selected and sequenced for characterization of th

SUBMITTER: Cunha MDP 

PROVIDER: S-EPMC7617034 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature