Changes in colorectal cancer incidence in seven high-income countries: a population-based study.

ABSTRACT:

Background

The overall incidence of colorectal cancer is decreasing in many high-income countries, yet analyses in the USA and other high-income countries such as Australia, Canada, and Norway have suggested increasing incidences among adults younger than 50 years. We aimed to examine longitudinal and generational changes in the incidence of colon and rectal cancer in seven high-income countries.

Methods

We obtained data for the incidence of colon and rectal cancer from 21 population-based cancer registries in Australia, Canada, Denmark, Norway, New Zealand, Ireland, and the UK for the earliest available year until 2014. We used age-period-cohort modelling to assess trends in incidence by age group, period, and birth cohort. We stratified cases by tumour subsite according to

SUBMITTER: Araghi M 

PROVIDER: S-EPMC7617144 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature