Pathways of clathrin-independent endocytosis.

ABSTRACT: There are numerous ways that endocytic cargo molecules may be internalized from the surface of eukaryotic cells. In addition to the classical clathrin-dependent mechanism of endocytosis, several pathways that do not use a clathrin coat are emerging. These pathways transport a diverse array of cargoes and are sometimes hijacked by bacteria and viruses to gain access to the host cell. Here, we review our current understanding of various clathrin-independent mechanisms of endocytosis and propose a classification scheme to help organize the data in this complex and evolving field.

SUBMITTER: Mayor S 

PROVIDER: S-EPMC7617177 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature