T₁ and T₂ measurements of the neonatal brain at 7 T.

ABSTRACT:

Purpose

To determine the expected range of NMR relaxation times (T₁ and T₂) in the neonatal brain at 7 T.

Methods

Data were acquired in a total of 40 examinations on infants in natural sleep. The cohort included 34 unique subjects with postmenstrual age range between 33 and 52 weeks and contained a mix of healthy individuals and those with clinical concerns. Single-slice T₁ and T₂ mapping protocols were used to provide measurements in white matter, cortex, cerebellum, and deep gray matter. Automatic image segmentation of a separate T₂-weighted brain volume was used to define regions of interest for analysis.

Results

Linear regression was used to estimate relaxation times at term equivalent age (40 weeks postmenstr

SUBMITTER: Mahmoud A 

PROVIDER: S-EPMC7617262 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature