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On the Environmentally Friendly Synthesis of 2-Hydroxyethyl Furan-5-Carboxylic Acid (MHEF) and bis(2-Hydroxyethyl) Furan-2,5-Dicarboxylate (BHEF).


ABSTRACT: To better understand how the biocatalyzed depolymerization of polyesters works, model molecules are needed to develop activity assays and determine enzymatic kinetic parameters. In this communication the chemical synthesis and characterization of 2-hydroxyethyl furan-5-carboxylic acid and bis(2-hydroxyethyl) furan-2,5-dicarboxylates as potential model molecules to further study the enzymatic depolymerization of poly(ethylene furanoate) was investigated.

SUBMITTER: Raboni F 

PROVIDER: S-EPMC7617567 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature

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On the Environmentally Friendly Synthesis of 2-Hydroxyethyl Furan-5-Carboxylic Acid (MHEF) and bis(2-Hydroxyethyl) Furan-2,5-Dicarboxylate (BHEF).

Raboni Francesco F   Oliveri Andrea A   Rocca Valeria Marisa VM   Moni Lisa L   Kumar Virender V   Varrone Cristiano C   Pellis Alessandro A  

ChemistryOpen 20250128 8


To better understand how the biocatalyzed depolymerization of polyesters works, model molecules are needed to develop activity assays and determine enzymatic kinetic parameters. In this communication the chemical synthesis and characterization of 2-hydroxyethyl furan-5-carboxylic acid and bis(2-hydroxyethyl) furan-2,5-dicarboxylates as potential model molecules to further study the enzymatic depolymerization of poly(ethylene furanoate) was investigated. ...[more]

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