Cognitive behavioural therapy for severe fatigue following COVID-19 in adolescents: a serial single-case observational study of five consecutively referred patients.

ABSTRACT:

Background

Severe fatigue following COVID-19 is a debilitating symptom in adolescents for which no treatment exists currently.

Aims

The aim of this study was to determine the effectiveness and feasibility of cognitive behavioural therapy (CBT) for severe fatigue following COVID-19 in adolescents.

Method

A serial single-case observational design was used. Eligible patients were ≥12 and <18 years old, severely fatigued and ≥6 months post-COVID-19. Five patients, consecutively referred by a paediatrician, were included. The primary outcome was a change in fatigue severity, assessed with the fatigue severity subscale of the Checklist Individual Strength, 12 weeks after the start of CBT, tested with a permutation distancing two-phase A-B test. Secondary outcomes were the p

SUBMITTER: Kuut TA 

PROVIDER: S-EPMC7617664 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature