Prediction of individualised 6-month mortality risk in opioid use disorder.

ABSTRACT:

Background

People with opioid use disorder (OUD) have substantially higher standardised mortality rates compared with the general population. However, lack of individualised prognostic information presents challenges in personalisation of addiction treatment delivery.

Aims

To develop and validate the first prognostic models to estimate 6-month all-cause and drug-related mortality risk for people diagnosed with OUD using indicators recorded at baseline assessment in addiction services in England.

Method

Thirteen candidate prognostic variables, including sociodemographic, injecting status and health and mental health factors, were identified from nationally linked addiction treatment, hospital admission and death records from 1 April 2013 to 1 April 2022. Multivariable

SUBMITTER: Roberts E 

PROVIDER: S-EPMC7617949 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature