Generalizability of Blood Pressure Lowering Trials to Older Patients: Cross-Sectional Analysis.

ABSTRACT:

Background/objectives

Randomized controlled trials are used to inform clinical guidelines on the management of hypertension in older adults, but it is unclear to what extent these trials represent the general population attending routine clinical practice. This study aimed to define the proportion and characteristics of patients eligible for hypertension trials conducted in older people.

Design

Cross-sectional study.

Setting

A total of 24 general practices in England.

Participants

Anonymized electronic health record data from all individuals aged 80 and older.

Measurements

Descriptive statistics were used to define the proportion and characteristics of patients eligible for two previous medication intensification trials (HYVET, SPRINT) and one medication

SUBMITTER: Sheppard JP 

PROVIDER: S-EPMC7618156 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature