Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD.

ABSTRACT:

Background

Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in such persons currently exist. The photovoltaic retina implant microarray (PRIMA) system combines a subretinal photovoltaic implant and glasses that project near-infrared light to the implant in order to restore sight to areas of central retinal atrophy.

Methods

We conducted an open-label, multicenter, prospective, single-group, baseline-controlled clinical study in which the vision of participants with geographic atrophy and a visual acuity of at least 1.2 logMAR (logarithm of the minimum angle of resolution) was assessed with PRIMA glasses and without PRIMA glasses at 6

SUBMITTER: Holz FG 

PROVIDER: S-EPMC7618305 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature