Hybrid Closed-Loop Therapy in Adults with Type 1 Diabetes in England: Long-Term Outcomes from a Real-World Observational Study.

ABSTRACT: Objective: To evaluate longitudinal real-world outcomes in adults with type 1 diabetes initiating hybrid closed loop (HCL). Methods: Adults with type 1 diabetes, managed with an insulin pump and intermittently scanned continuous glucose monitoring with hemoglobin A1c (HbA1c) ≥8.5% (69 mmol/mol), were started on HCL between August and December 2021 as part of the National Health Service England HCL pilot. We collected outcomes, including change in HbA1c, sensor glucometrics, Gold score (hypoglycemia awareness), diabetes distress score, acute event rates, and user opinion of HCL. Results: In total, 420 HCL users across 30 diabetes centers in the United Kingdom were included (median age 40 [interquartile range or IQR 29-50] years, 68% female, 85% Whit

SUBMITTER: Liarakos AL 

PROVIDER: S-EPMC7618701 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature