Factors associated with drug shortages in Canada: a retrospective cohort study.

ABSTRACT:

Background

To monitor the magnitude of the drug shortage problem in Canada, since 2017, Health Canada has required manufacturers to report drug shortages. This study aimed to identify the factors associated with drug shortages in Canada.

Methods

We conducted a retrospective cohort study of all prescription drugs available on the market between Mar. 14, 2017, and Sept. 12, 2018, in Canada. All drugs of the same active ingredient, dosage form, route of administration and strength were grouped into a "market." Our main outcome was shortages at the market level, determined using the Drug Shortages Canada database. We used logistic regression to identify associated factors such as market structure, route or dosage form, and Anatomic Therapeutic Chemical (ATC) classification.

R

SUBMITTER: Zhang W 

PROVIDER: S-EPMC7641197 | biostudies-literature | 2020 Jul-Sep

REPOSITORIES: biostudies-literature