Liver injury with COVID-19 based on gastrointestinal symptoms and pneumonia severity.

ABSTRACT:

Background/aim

The coronavirus disease 2019 (COVID-19) had become a big threat worldwide. Liver injury is not uncommon in patients with COVID-19, and clarifying its characteristics is needed. This study aimed to identify factors associated with liver injury and to develop a new classification of predictive severity in patients with COVID-19.

Methods

Confirmed patients with COVID-19 (n = 60) were recruited retrospectively from Musashino Red Cross Hospital. The factors of liver injury especially on the elevation of liver enzymes (aspartate aminotransferase [AST] and alanine aminotransferase [ALT]) were analyzed. Grading was assessed according to the Common Terminology Criteria for Adverse Events (CTCAE) version 5.0.

Results

During a median hospitalization follow-up of 1

SUBMITTER: Kaneko S 

PROVIDER: S-EPMC7641400 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature